I have had similar experiences too, but my breaks now tend to be perhaps 4 or 5 days maximum. It is good for me to get out of the routine. I found in the past when taking a week or more I would start thinking about the strangers I was having such close contact with, people who I knew nothing about. BUT I know I will be fine once I get into it, so I enjoy the break in the moment then look forward to first client/or online/phone chat session.
Also since I started remote online, cam, phone chat, video making I sometimes simply have just an in-person break - work online only so I am still engaging in one (or two) senses.