I and others on here have asked questions about best lubes on here and there are lots of threads on the subject - I'm not starting another of those about which is best and what is your fave - we all seem to have preferences
My point is that besides none of them working well (slipiness goes after a few minutes of friction and they go sticky and drag), I have come to the conclusion that they all generally make me sore and I'm certain that using a big application frequently gives be BV. Anyhow, out of frustration I asked my GP for advice when I was there (understanding female GP who knows what I do). She told me that there is now evidence that they are bad for your vagina particularly in sex work applications. I dont offer PIV sex but I do toy and intimate shows that have previously used a lot of lube (eg 1 big tube a week). She said that they can irritate the vagina and cause upset in acid balance. She says the best lube is your own that you make when aroused and if you need more, use proper vaginal moisturiser - but even some of those can be damaging. She says it can also be irritating if you use it on your bum for anal work.
I did my own google search (search for intimate lube safety) and the results are quite shocking. Search it for yourself.
My GP also said that the makers could do a better job and that at the moment none are perfect and some of the big sellers are the worst.
I can make myself wet in my private life and it happens now and then with bookings - but I'm worried that I'm running out of juice - literally!