hi celebate
i don't really know, but i think there might be different agencies that tailor for different tastes, from that perspective i would say it is probably worth shopping around.
depending how you feel of rejections, it might be worth applying for them. i would guess looking on their site and if they do have women with sizes over 12 and 14 than its worth applying.
with agency work in general, in another post there was a link posted i find quite helpful, about what to look out in an agency.
http://www.praedstreetproject.org.uk/safety-escort.htm (alex posted it)
i personally would feel that it would be important that i could turn down a client for whatever reason, for example if i don't feel comfortable or something happens on the booking, i think for my personal and emotional health that would be important for me.
i hope that was of any use for you