Incall: it's your space, you know where things are, you know things are clean (and, if you've any sensitivities to pet fur or whatever, it's ok), you know there's no-one hiding in another room, you know you're not going to be confronted with evidence of their 'other life' ("we have to be quiet, because of the kids"), and if they don't show, you've not had a wasted journey.
Penny's covered most of the security aspects. Definitely yes to you making a call on their arrival, which they hear, saying they've arrived. Make it clear in that call that the other end has their contact details too (the killers of one male escort nicked his SIM card, expecting that to remove all evidence of the number they'd used to call him).
Outcall: you don't have to find somewhere to work from or worry about what the neighbours think. There must be other advantages or I wouldn't do it! Ah yes, you don't need to keep somewhere tidy, and you know that no-one's going to hang around afterwards to follow / rob you.
As you can see, some very lovely people successfully do incall from their own home, but personally I wouldn't consider it for a second.
In my view, if you can't afford to hire somewhere for incall work, you're not charging enough. (Plus the expense is tax deductable!)
Can clients come to the house without neighbours wondering what's going on? Penny's got one story. Another thing to consider telling the neighbours is 'counselling' - it explains why they see men arriving looking nervous and leaving looking happier
If you say 'massage', they'll want one, so you need to be good at it, and they will wonder why you don't have (m)any female clients.
How are you going to keep them out of areas you don't want them to see or accidentally breaking things you don't want broken?
When they look in your bathroom cabinet - and some of them will - what are they going to see? A prescription with your name? When they look in your laundry pile, what will they find? Your underwear?
If one robbed you, what else would they get away with?
If they turned up another time, who would they find? If you've got children living there, this is why I'd suggest it's a complete no-no, but again, I know people who do it.
If they told their mates, who would turn up, typically after the pubs are shut, loudly demanding a shag?
If they're ill, it'll be your floor they're sick over. Your toilet paper they wipe their bum on (and use all of, blocking your toilet). Your cups and glasses they break.
If you don't have a spare bedroom, it can be incredibly hard to forget that it was your bed - the space will always be 'theirs' as well as 'yours'.
But having said all that, if someone is determined to do it, never let them know it is your home: make up a story about it being a friends' (a couples!) house which you use during the day / evening when they're at work.
That way, they think that
a) if they show up later they will not find you
b) if they show up later, they will find a man
c) the stray bits of paper they find - and they will look, given the chance - with your name on it is not your name, but someone else's
d) any little "keepsakes" they take (panties, perfume - not necessarily valuable but souvenirs or wanking accessories when reliving the time with you) are not yours.
Even with that, at some point, someone will come back one night and see.
Personally, I'd be happier doing streetwork than working at home, and that's saying something. But I know someone who enjoys streetwork, so it's what you're comfortable with that counts.