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Author Topic: Would you take Daily anti-hiv medication for prevention?  (Read 1792 times)

woofy86

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Would you take Daily anti-hiv medication for prevention?
« on: 09 July 2013, 12:42:04 pm »
Just curious to anyone who is at high risk. Just a simple question... Would you take PreP medication to prevent HIV infection? In order to get good protection it must be taken daily, at same time and depending  on the drug being used can have between 63% to 90% prevention. Tho  other factors come into if something resistant e.t.c But it can have side effects for some people... So would you do it?
« Last Edit: 09 July 2013, 12:49:26 pm by woofy86 »

ana30

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #1 on: 09 July 2013, 12:59:43 pm »
If I were at high risk I would take such medication (ej's: I was a heroin addict, my partner had HIV, I went to sex clubs every weekend and had tons of bareback sex with lots of people etc...) But because I'm a very low risk and always use condoms (even with partners) I'm obviously NOT going to take it. I'm more concerned about hepatitis, herpes, gonorrhea or a myriad of other diseases.
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amy

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #2 on: 09 July 2013, 01:10:37 pm »
As Ana says, I doubt there are many (if any) people here belonging to many (or any) high risk groups, and quite the opposite in many cases. Woofy, I have to ask, what on earth does this have to do with sex work? By that I mean why, despite all evidence to the contrary) have you assumed that sex workers are at a high risk of HIV?
« Last Edit: 09 July 2013, 01:13:21 pm by amy »

Vampera

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #3 on: 09 July 2013, 01:54:06 pm »
The one thing you haven't mentioned is that it has DREADFUL side effects.....terrible sickness and vomiting and diorrhoea and other side effects....Its not something that you can take lightly and think it won't affect you....

And I agree....I'm not a high-risk person....I've never had an STD in my Life let alone put myself at Risk of HIV...
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woofy86

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #4 on: 09 July 2013, 02:09:40 pm »
Was reading article about some doctor who says  they would prescribe PreP for men who sex with men, plus they are doing  a trail in London for at high risk people, which includes escorts, but I think it people who regularly have  unprotected sex.  :-\

Sorry, if I offended anyone. I would take it, truvada, doesn't says side effects are rare. Just, I guess for peace of mind.

xw5

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #5 on: 09 July 2013, 04:42:04 pm »
There's so much wrong with this as an idea, that it's difficult to know where to start.

I'd bet he's not suggesting prescribing on the NHS = it will not be cheap.

It won't protect against other STIs.

It will help build up HIV's resistance to drugs.

Even 90% effective is not something I'd want to rely on. If we look at 'HIV+ cum in the bum' transmission chances, then the high end of the 'per time' estimates is 3%. Do it a hundred times, and you're looking at a 95% chance of ending up HIV+. Make it ten times less (i.e. it's 90% effective), and you're still looking at more than a 25% chance of being infected. If it turns out to be only 63% effective, then it's a 67% chance...

= this is something that will not very effectively delay infection, at great cost, not stop it.

Obviously, I can see why the drug companies have an interest in a trial: they'd love lots more people taking expensive drugs. I can even see why an ethics committee would say ok. But it's the equivalent of trying to reduce lung cancer by giving smokers a lung transplant every few years rather than helping them stop smoking...
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sweet jane

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #6 on: 09 July 2013, 08:45:49 pm »
truvada, doesn't says side effects are rare.

Erm...beg to differ, I've been care giver for some one on Truvada and they felt pretty ill - fatigue, stomach upsets.

The Bachelor

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #7 on: 09 July 2013, 08:48:02 pm »
Obviously, I can see why the drug companies have an interest in a trial: they'd love lots more people taking expensive drugs. I can even see why an ethics committee would say ok. But it's the equivalent of trying to reduce lung cancer by giving smokers a lung transplant every few years rather than helping them stop smoking...
That's what it's all about...HIV+ people are providing these companies with BILLIONS in revenue each year.

I personally do not believe (from all my studies) HIV alone, in itself...is as bad as we are lead to believe. I know this for a fact. I'm not going to go into it, but this is coming from a healthy person. But, what is bad are the medications being given to people to take every single day or as 'prevention'. Your liver was not designed to be popping pills (with the exception of supplements that are already produced naturally in the body) everyday. You'll die of organ failure.

In addition, just because I believe in what I do, I don't believe in however bareback sex. It's been shown that semen (cum) is a immune-suppresent, for 1. And # 2, all those other diseases are nothing to play with either. But I don't believe in a healthy person going on any kind of HIV medications just because everyone else is doing it. It gives you stick legs, and sunken cheeks.
« Last Edit: 09 July 2013, 08:51:41 pm by Blaine »

woofy86

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #8 on: 09 July 2013, 09:55:23 pm »
Well it's true that drug companies are making money but cause of the cost it's not going to be approved by the government. It been approved by the FDA. This is why drug companies are trying to fight  India and Thailand  over the cheaper generic versions cause they are ripping people off and good as killing people who can't afford. As for the side effects it very dependant on the person, and if a person was going to be prescribed this by a doctor, a person must not have liver disease, bone density problems.

Drug resistance is a result of people not sticking to the medications (people already infected) or not following directions. The sad thing is if everyone got tested regularly there would be a major decline in HIV because they could be put on medication, which significantly lowers a negative persons chance of becoming infected.

I am not blindly just making up a thread, many doctors around the world are now seeing PreP, early treatment and other forms of prevention as a means of stopping the epidemic. And many countries around the world are holding PreP trials which are showing more than promising results. It's not an illusion.

I have seen what H.I.V  or AIDS can do as I grew up in  Southern Africa when people were dropping like flies in mid to late 90's. I have had family members who have pass away from Aids and currently on treatment in Africa, all straight. H.I.V  is a very touchy subject, even when i bring it up with other gay men when meeting for a drink everyone tries to avoid the subject or get offended ( my experience, don't know yours) And yes you can catch other S.T.D's if you don't use condoms e.t.c But if I am sleeping with a higher than normal amount of people, even with condoms, I do feel it does increase my risk compared to the normal person.

I do agree, that the general population should not regularly use this, just people in higher risk and people who it won't harm their health in the long run.


http://www.avert.org/pep-prep-hiv.htm

Here's a link explaining PrEP and the studies associated with it.


http://www.thebody.com/content/71466/this-prep-ed-life-damon-jacobs-on-sex-and-dating-i.html?getPage=1

A link of a man on PrEP as mean of prevention/
« Last Edit: 09 July 2013, 09:59:38 pm by woofy86 »

xw5

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Re: Would you take Daily anti-hiv medication for prevention?
« Reply #9 on: 09 July 2013, 10:46:52 pm »
The guy in the article loves talking about 99% effectiveness, but if you look at the basic study, it doesn't match up.

It was another case of 'cheap studies in other people's misery' - they recruited about 2,500 men, but only 200ish from the US. The rest were from places like Peru and Equador, with some from Brazil, South Africa and Thailand. They gave half a sugar pill (this lot had less nausea and less weight loss, typical side-effects of the actual drugs) and half the drugs. All of them got some health promotion, and this contributed to an increase in safer sex. After a year or so - there was a big drop off in use - the effectiveness of the drug in preventing HIV transmission was shown to be just a "disappointing" 44%. They had the same rates of other STIs.

Given what I reckon above regarding it being a delay effect, a shitload of what could be in many of the places otherwise unattainable drugs and decent medical care got a pointless delay in HIV infections. They'd have been better off spending the money on the health promotion and medical care to more people.

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